Smart manufacturing (SM) is a powerful disruptive technology-driven approach that exploits Internet-connected machinery to monitor the production process. The goal of center for Smart Manufacturing (CSM) is to identify opportunities for automating operations and use data analytics to improve manufacturing performance. It has a great potential to reform the contemporary competitive scenario and produce a new set of market leaders who can drive the economy to greater heights. CSM will support startups in (i) integration & implementation of Industrial internet of things (IIoT) for agnostic sectors, (ii) Artificial Intelligence for Innovation & Manufacturing, (iii) R&D for blockchain majorly for food & beverage, medical and even mobility & transportation, (iv) application of Industrial Robotics, (v) implementation of Digital Twins.